Ústavní schůzka Pondělí 5. ledna 2015

Our institute was successful in obtaining funding – at least most from BC, and not only from Czech sources, but also from highly competitive international sources, such as f.e. Astrid Holzer – HORIZON 2020 (ParaFishControl) Jula Lukeš et al. – GAČR grant Tomáš Scholz et al. – GAČR grant Martin Kváč et al. – GAČR grant Libor Grubhoffer et al. – GAČR grant Libor Grubhoffer + Petr Kopáček et al. – EU - Antidote Miroslav Oborník et al. – GAČR grant Zdeněk Paris – GAČR grant (post-doc) Veronika Urbanová – GAČR grant (post-doc) Astrid Holzer – contract from Norvegian fisheries Jana Nebesářová – Czech-BioImaging

2015 – 7 GAČRů!! ( z celkových 11 na BC) 2014 – 3 GAČRy 2013 – 4 GAČRy 2012 – 11 GAČRů 2011 – 6 GAČRů ROZPOČET ÚSTAVU 2014 Celkem 118 mil, z toho režie 47 mil (40%), 37% mezd placeno z režie, 63% mezd z grantů (proto tolik odměn – možná až moc, viz další slide!) 2013 Celkem 121 mil, z toho režie 47 mil (39%) 2012 Celkem 114 mil, z toho režie 46 mil (40%) 2011 Celkem 97 mil, z toho režie 53 mil (55%)

Papers with IF > 8488 Papers with IF Chapters463 Monographs150 Suma IF327,48408,38399,48 VĚDECKÁ PRODUKCE - SROVNÁNÍ = ŠPATNÝ ROK (BAD YEAR)!!! We cannot afford another one like this…

2014Relative papers with IF*Relative IF*Papers with IF # IF # Lukeš lab13,839,91955,35 Oborník lab2,04,9611,32 Zíková lab0,0 00 Paris lab0,0 00 Horák lab0,0 00 Grubhoffer/Rudenko lab12,851,01764,51 Kopáček lab1,35,0517,95 Růžek lab10,446,71457,45 Kotsyfakis lab6,329,3731,85 Hajdušek lab1,24,1413,46 Holzer lab8,819,61125,26 Kváč lab13,038,21645,22 Scholz lab36,058,63863,97 Štefka lab4,515,8517,53 Pomajbíková lab1,54,4618,27 Nebesářová lab2,97,6616,91 * Relativized according to number of authors from individual labs; # I find the right-most number somewhat more important, because we don´t want to punish collaboration (too much)

Relativized according to number of authors from individual labs; *2014 Relative IF No. Researchers + Posdocs* 2014 ( ) 2013 ( ) 2012 ( ) Lukeš lab 939,997,9112,7 Oborník lab 64,915,742,9 Zíková lab 30,0 3,33,3 Paris lab 10,0-- Horák lab 10,010,1- Grubhoffer/Rudenko lab 551,024,74,5 Kopáček lab 45,06,74,7 Růžek lab 346,721,512,4 Kotsyfakis lab 129,3 47,0 Hajdušek lab 24,10,0- Holzer lab 719,622,228,0 Kváč lab 338,245,627,5 Scholz lab 858,670,876,6 Štefka lab 415,848,75,2 Pomajbíková lab 14,41,84- Nebesářová lab 37,618,022,8

Papers with IF > 4 (IF > 8) No. Researchers + Posdocs* 2014 ( ) 2013 ( ) 2012 ( ) Lukeš lab 92 (1)15 (3)14 (7) Oborník lab 604 (2)6 (3) Zíková lab 3000 Paris lab 10-- Horák lab 102 (1)- Grubhoffer/Rudenko lab 52 (1) 1 Kopáček lab 4111 Růžek lab 3 1 (1)21 Kotsyfakis lab 14 (1) 6 Hajdušek lab 200- Holzer lab 7212 (1) Kváč lab 3310 Scholz lab 8221 Štefka lab 412 (1)0 Pomajbíková lab 110- Nebesářová lab 3003 *2014

Editorial Material: Cabezas-Cruz A., Valdés J.J., de la Fuente J. 2014: Cancer research meets tick vectors for infectious diseases. Lancet Infectious Diseases 14: 916–917. IF = 19,446 Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.-A., Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J., Katinka M., Jabbari K., Aury J.-M., Campbell D.A., Cintron R., Dickens N.J., Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukeš J., Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F., Wincker P., Dollet M. 2014: The streamlined genome of Phytomonas spp. relative to human pathogenic kinetoplastids reveals a parasite tailored for plants. PLOS Genetics 10: e IF = 8,167 Schnettler E., Tykalová H., Watson M., Sharma M., Sterken M.G., Obbard D.J., Lewis S.H., McFarlane M., Bell-Sakyi L., Barry G., Weisheit S., Best S.M., Kuhn R.J., Pijlman G.P., Chase-Topping M.E., Gould E.A., Grubhoffer L., Fazakerley J.K., Kohl A. 2014: Induction and suppression of tick cell antiviral RNAi responses by tick-borne flaviviruses. Nucleic Acids Research 42: 14. IF = 8,808 Waisberg M., Molina-Cruz A., Mizurini D.M., Gera N., Sousa B.C., Ma D., Leal A.C., Gomes T., Kotsyfakis M., Ribeiro J.M., Lukszo J., Reiter K., Porcella S.F., Oliveira C.J., Monteiro R.Q., Barillas-Mury C., Pierce S.K., Francischetti I.M. 2014: Plasmodium falciparum Infection Induces Expression of a Mosquito Salivary Protein (Agaphelin) That Targets Neutrophil Function and Inhibits Thrombosis without Impairing Hemostasis. PLoS Pathogens 10: e IF = 8,057 Papers with IF > 8

Flegontov P., Votýpka J., Skalický T., Logacheva M.D., Penin A.A., Tanifuji G., Onodera N.T., Kondrashov A.S., Volf P., Archibald J.M., Lukeš J. 2013: Paratrypanosoma Is a Novel Early-Branching Trypanosomatid. CURRENT BIOLOGY 23: 1787–1793. IF = 9,494. Husník F., Nikoh N., Koga R., Ross L., Duncan R. P., Fujie M., Tanaka M., Satoh N., Bachtrog D., Wilson A. C. C., von Dohlen C. D., Fukatsu T., McCutcheon J. P. 2013: Horizontal gene transfer from diverse bacteria to an insect genome enables a tripartite nested mealybug symbiosis. CELL 153(7): 1567–1578. IF = 31,957 Janouškovec J., Horák A., Barott K.L., Rohwer F.L., Keeling P.J. 2013: Environmental distribution of coral- associated relatives of apicomplexan parasites. ISME JOURNAL 7: 444–447. IF = 8,951 Janouškovec J., Sobotka R., Lai D.-H., Flegontov P., Koník P., Komenda J., Ali S., Prášil O., Pain A., Oborník M., Lukeš J., Keeling P.J. 2013: Split photosystem protein, linear-mapping topology and growth of structural complexity in the plastid genome of Chromera velia. MOLECULAR BIOLOGY AND EVOLUTION 30: 2447– IF = 10,353 Kořený L., Oborník M., Lukeš J. 2013: Make it, take it or leave it: Heme metabolism of parasites. PLOS PATHOGENS 9: e IF = 8,136 Ma D., Mizurini D.M., Assumpçăo T.C.F., Li Y., Qi Y., Kotsyfakis M., Ribeiro J.M.C., Monteiro R.Q., Francischetti I.M.B. 2013: Desmolaris, a novel Factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis. BLOOD 122: 4094–4106. IF = 9,060 Preston S.G., Majtán J., Kouremenou C., Rysnik O., Burger L.F., Cabezas-Cruz A., Guzman M.C., Nunn M.A., Paesen G.C., Nuttall P A., Austyn J.M Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses. PLOS PATHOGENS 9(6): e IF = 8,136 Ward J.D., Bojanala N., Bernal T., Ashrafi K., Asahina M., Yamamoto K.R. 2013: Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development. PLOS GENETICS 9: e IF = 8,517 Papers with IF > 8 = but 2013!

General comparison of Czech research with Western Europe and USA – still not good enough… We need to double our production in order to close the gap with the best EU countries, not necessarily more papers, but higher impact and more respected = cited papers On top of that – CAS/AVCR has to produce at least double than the best Czech We want Western standards from SoS, grant agencies, suppliers etc., but first of all, we shall deliver according to them… Slide from last year – apparently did not stimulate much…

Prémie Otto Wichterleho – Jan Štefka Post-doc z centrálních zdrojů AV – Zoltan Fussy dostal, Jana Veselá to bohužel nedostala 4. ročník soutěže Jihočeská ratolest – M+M Jirků A lot of popularization of the institute Thanks to mostly Brian P., we have a complete list of equipment Some additional good stuff

Science citation index (without primary autocitation) name / yearPhD Miroslav Oborník Julius Lukeš František Moravec Tomáš Scholz David Modrý Aleš Horák Jan Votýpka Milan Jirků Michalis Kotsyfakis Libor Grubhoffer Radek Šíma Petr Kopáček Martin Kváč Václav Hypša Nataliia Rudenko Jan Kopecký Alena Panicucci Zíková Bohumil Sak Maryna Golovchenko 4480 Jiří Vávra Ivan Fiala Aneta Kostadinova Marie Vancová Daniel Růžek Daniel Sojka Jana Nebesářová Jindřich Chmelař Miloslav Jirků Luděk Kořený Jiří Salát Anna Faltýnková Klára J. Petrželková Ondřej Hajdušek Roman Kuchta Silvie Trantírková (Foldýnová) Martin Kostka Some additional good stuff Citations are increasing, especially important to see it happening with the young guys – if we want to be eligible for big EU funding, this is a must…

SOCIAL FUND ( SOCIAL FUND (použití prostředků) Příspěvek na stravování (úvazek 3/8) Půjčky na pořízení bytu a jeho vybavení – zastaveno! Finanční pomoc v mimořádných situacích Významná životní výročí Kurzy angličtiny (4 × 60 minut/týdně) Vánoční večírek – 45 tis.

What expects us in 2015… Big evaluation of the institute Animal house construction shall finish in September Discussion on who will move there Insulation of the building project Lower total budget (big projects such as Praemium, Modbiolin and Bioglobe will terminate) 10 US students in summer Better scientific production – needed!!!