Cvičení z molekulární biologie Blokově v zápočtovém tydnu útery/středa 6.1. a 7.1. 2015 2 dny, každý den cca 4 hodin (9 – 13) studenti se rozdělí do skupin referát o životě a práci vědců, kteří obdrželi Nobelovu cenu 30 minut přednáška + 10 minut diskuze FORMÁT prezentace bude odrážet život a klíčové okamžiky dané vědecké kapacity rozbor experimentů, které vedly k danému mimořádnému objevu sdělení, jak daný objev změnil molekulární biologii a kam ji posunul

Témata ke cvičení z molekulární biologie 6.7. : The Nobel Prize in Physiology or Medicine 2009 Elizabeth H. Blackburn, Carol W. Greider and Jack W. Szostak "for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase” Bystřická, Weberová The Nobel Prize in Chemistry 2009 Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath "for studies of thern structure and function of the ribosome” Veronika Blažková a Anna Humlová The Nobel Prize in Chemistry 2008 Osamu Shimomura, Martin Chalfie and Roger Y. Tsien "for the discovery and development of the green fluorescent protein, GFP” Tereza Pospíšilová a Jana Piherová The Nobel Prize in Physiology or Medicine 2006 Andrew Z. Fire and Craig C. Mello "for their discovery of RNA interference - gene silencing by double-stranded RNA" Boudová M.+ Krejčová G.

7.7. : The Nobel Prize in Chemistry 2006 Roger D. Kornberg "for his studies of the molecular basis of eukaryotic transcription" Zahrandíková, Stachová, Tvrdková The Nobel Prize in Physiology or Medicine 1999 Günter Blobel "for the discovery that proteins have intrinsic signals that govern their transport and localization in the cell” Kvardová, Kubičková A. The Nobel Prize in Physiology or Medicine 1993 Richard J. Roberts and Phillip A. Sharp "for their discoveries of split genes" Klimešová, Berková The Nobel Prize in Chemistry 1993 "for contributions to the developments of methods within DNA-based chemistry" Kary B. Mullis - "for his invention of the polymerase chain reaction (PCR) method” Helena ŠOKČEVIČOVÁ, Martina JEDLIČKOVÁ Michael Smith - "for his fundamental contributions to the establishment of oligonucleotide-based, site-directed mutagenesis and its development for protein studiesThe Nobel Prize in Chemistry 1989 Sidney Altman and Thomas R. Cech „for their discovery of catalytic properties of RNA” Morávková 7.7. :

The Nobel Prize in Physiology or Medicine 1983 Barbara McClintock "for her discovery of mobile genetic elements” Jaroslava Blažková, Lydie Plačková, Veronika Hejdová The Nobel Prize in Physiology or Medicine 1978 Werner Arber, Daniel Nathans and Hamilton O. Smith "for the discovery of restriction enzymes and their application to problems of molecular genetics” Michaela Kunzová, Pavla Šnebergová The Nobel Prize in Chemistry 1980 Paul Berg - "for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA" Walter Gilbert and Frederick Sanger - "for their contributions concerning the determination of base sequences in nucleic acids” Bártová, Kubíčková M. The Nobel Prize in Physiology or Medicine 1968 Robert W. Holley, Har Gobind Khorana and Marshall W. Nirenberg "for their interpretation of the genetic code and its function in protein synthesis” Šimková, Štefková, Mašková The Nobel Prize in Chemistry 1958 and 1980 Frederick Sanger "for his work on the structure of proteins, especially that of insulin” "development of chemical and biological analyses of DNA structure” Marie Bártová, Kubíčková M. spojeno