Virus Authors (alphabetically): Hrubý Jakub Moráň Lukáš Sasínek Filip Gymnázium, třída Kapitána Jaroše 14, Brno.

Prezentace na téma: "Virus Authors (alphabetically): Hrubý Jakub Moráň Lukáš Sasínek Filip Gymnázium, třída Kapitána Jaroše 14, Brno."— Transkript prezentace:

1 Virus Authors (alphabetically): Hrubý Jakub Moráň Lukáš Sasínek Filip Gymnázium, třída Kapitána Jaroše 14, Brno

2 Table of contents General characteristics History Replication Selected diseases Usage in medicine

3 What is a virus ? Non-cellular parasitic structure Own genome with genes No metabolism or source of energy Organisms at the edge of life Need of host cell

4 Structure Virion – viral particle Two or three parts Nucleic acid DNA or RNA Capsid Protein coat Envelope Made of lipids

5 Discovery 1892 - Dimitri Iosifovich Ivanovsky Tobacco mosaic Disease is not caused by a bacteria 1898 - Martinus Wilhelm Beijerinck First use of the word virus Virology

6 Replication Entering the host cell Changing the metabolism Creating of new viral components Lytic cycle Lysogenic cycle

7 Selected diseases Smallpox Variola Transmission Airborne, face-to-face Symptoms Fever, muscle pain, macules – little spots Fatal in most cases Eradicated Declared by WHO in 1980 /last case in 1975/

8 Selected diseases SARS /Severe acute respiratory syndrome/ SARS-CoV Transmission Airborne Symptoms Fever, headache, cough, pneumonia Outbreak in 2002 China, then other countries

9 Selected diseases AIDS /Acquired Immune Deficiency Syndrome/ HIV Reverse transcriptase Transmission Blood, sexual intercourse Symptoms Flu after infection Immune system break down T - lymphocytes /2008/

10 Usage in medicine Retro virus Reverse transcription (RNA  DNA) Gene therapy Viral vectors Complications Pathogenicity Viability of adjusted cells Expensive procedure

11 Conclusion 1898 – discovery of viruses Non-cellular parasitic structure 3 parts Nucleic acid, protein coat and lipid envelope Need of host cell Importance in the future Antibiotics do not work for viral diseases !

12 Interactive part The Quiz

13 Resources RNDr. KOČÁREK, Eduard, Ph.D.: Genetika, Praha, nakladatelství Scienta, 2008, 211 stran, ISBN 978-80-869960-36-4 PROF. RNDr. ROSYPAL, Stanislav, DrSc.: Bakteriologie a Virologie, Praha, nakladatelství Scientia, 1994, 67 stran, ISBN 80-85827-16-6 http://cs.wikipedia.org/wiki/Virus [cit. 2010-10-26  http://radim-kramar.byl.cz/Virologie.htm [cit. 2010-10-26  http://www.zdrava-rodina.cz/med/med998/med998_1.html [cit. 2010-10-26  http://genetika.wz.cz/viry.htm [cit. 2010-10-26  http://aidsblog.ihelpdesk.cz/index.php/2008/09/09/video-replikace-hiv [cit. 2010-10-26  http://biomikro.vscht.cz/documents/hygklinmik/klinika8.pdf [cit. 2010-10-26  http://botany.upol.cz/prezentace/sedlarova/MB_viry_t.pdf [cit. 2010-10-26  http://www.biology.webz.cz/viry.php [cit. 2010-10-26  http://www.imaturita.cz/pdf/06biol.pdf [cit. 2010-10-26  http://en.wikipedia.org/wiki/Virus [cit. 2010-10-26 

14 Thank you for your attention