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ZveřejnilBarbora Simona Hrušková
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2014 CELL DIVISION Výukový materiál MB 04 - 94 Tvůrce: Mgr. Šárka Vopěnková Tvůrce anglické verze: ThMgr. Ing. Jiří Foller Projekt: S anglickým jazykem do dalších předmětů Registrační číslo: CZ.1.07/1.1.36/03.0005 Tento projekt je spolufinancován ESF a SR ČR
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entire cell = zygote zygote divides repeatedly developed cell differentiates > tissues > organs> organisms CELL DIVISION
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cells reproduce by division division is anticipated by chromosome division = replication of DNA PROKARYOTIC CELL DIVISION
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CELL CYCLE the life period of the cell from its origin up to the development of daughter cells the cell stops dividing > it accomplishes specific functions liver cell divides once a year neuron never divides the most cells of human body undergo about 50 divisions and then they die
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cell cycle - 2 main phases: 1) cell division a) nuclear division: mitosis or meiosis b) cell division 2) interphase 90% of whole cell cycle the cell grows up in the nucleus there is chromatin > replication of DNA interphase: G 1, S, G 2 phase CELL CYCLE
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1. replication of DNA 2. cell division cell cycle: sequence of processes from the first to the second division PROKARYOTIC CELL DIVISION
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REGULATION OF CELL CYCLE
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there are three of them: in the phases G1, G2, M cells of mammals – the point in the G1 phase is obviously the most important if the cell does not receive the signal „Ahead“ in G1 phase, it can get into G 0 phase. the most cells of our body are in this phase CHECKPOINTS
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INTERPHASE G1 phase metabolic activity by the isolation of the daughter cell the cell grows up synthesis of RNA and proteins main control nodal point S phase synthetic replications of DNA proceeds here: DNA replicates up to double amount > chromosome is doubled since then: created by a pair of sister chromatids the cell is actually tetraploid
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INTERPHASE G2 phase relatively short metabolic activity the cell grows up rapidly reduplication of organelles formation of structures necessary for the cell division
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INTERPHASE G0 phase G0 phase the phase when the cell does not divide any more ending of the cell cycle by differentiated cells the beginning is influenced by the control the beginning is influenced by the control nodal point placed in the beginning G1 phase fully differentiated cells (e.g.. neurons) do not divide any more on the contrary e.g. liver cells - hepatocytes are able to go from G0 phase do G1 phase to start dividing again in the case of need
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REGULATION OF THE CELL CYCLE it proceeds through specific compounds either stimulated and accelerated by the division (growth hormones, cytokinins) or, on the contrary, they inhibit, stop (lack of nutrients, cytostatics) all regulators influence the division in G1 phase = main control nodal point
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KUBIŠTA, Václav. Obecná biologie. Praha: Fortuna, 2000, ISBN 80-7168-714-6. CHALUPOVÁ - KARLOVÁ, Vlastimila. Obecná biologie. Olomouc: Nakladatelství Olomouc, 2010, ISBN 978-80-7182-282-0. ZÁVODSKÁ, Radka. Biologie buněk. Praha: Scientia, 2006, ISBN 80-86960-15-3. ROSYPAL, Stanislav. Nový přehled biologie. 1. vyd. Praha: Scientia, 2003, 797 s. ISBN 80-718-3268-5. JELÍNEK, Jan, Vladimír ZICHÁČEK a Miroslav ŠVÁTORA. Biologie pro gymnázia: teoretická a praktická část. 2. dopl. a rozš. vyd. Olomouc: Nakladatelství Olomouc, 1998, 551 s. ISBN 80-718-2050-4 SOURCES
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