Prezentace na téma: "Virus Authors (alphabetically): Hrubý Jakub Moráň Lukáš Sasínek Filip Gymnázium, třída Kapitána Jaroše 14, Brno."— Transkript prezentace:
Virus Authors (alphabetically): Hrubý Jakub Moráň Lukáš Sasínek Filip Gymnázium, třída Kapitána Jaroše 14, Brno
Table of contents General characteristics History Replication Selected diseases Usage in medicine
What is a virus ? Non-cellular parasitic structure Own genome with genes No metabolism or source of energy Organisms at the edge of life Need of host cell
Structure Virion – viral particle Two or three parts Nucleic acid DNA or RNA Capsid Protein coat Envelope Made of lipids
Discovery 1892 - Dimitri Iosifovich Ivanovsky Tobacco mosaic Disease is not caused by a bacteria 1898 - Martinus Wilhelm Beijerinck First use of the word virus Virology
Replication Entering the host cell Changing the metabolism Creating of new viral components Lytic cycle Lysogenic cycle
Selected diseases Smallpox Variola Transmission Airborne, face-to-face Symptoms Fever, muscle pain, macules – little spots Fatal in most cases Eradicated Declared by WHO in 1980 /last case in 1975/
Selected diseases SARS /Severe acute respiratory syndrome/ SARS-CoV Transmission Airborne Symptoms Fever, headache, cough, pneumonia Outbreak in 2002 China, then other countries
Selected diseases AIDS /Acquired Immune Deficiency Syndrome/ HIV Reverse transcriptase Transmission Blood, sexual intercourse Symptoms Flu after infection Immune system break down T - lymphocytes /2008/
Usage in medicine Retro virus Reverse transcription (RNA DNA) Gene therapy Viral vectors Complications Pathogenicity Viability of adjusted cells Expensive procedure
Conclusion 1898 – discovery of viruses Non-cellular parasitic structure 3 parts Nucleic acid, protein coat and lipid envelope Need of host cell Importance in the future Antibiotics do not work for viral diseases !
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